Monday, July 8, 2013

Prerequisites for Exploring Predictors of Chronic Atrial Fibrillation Recurrence After Ablation

Citation : Mahito Noro, MD, PhD

The ablation treatment for the atrial fibrillation extends to the persistent atrial fibrillation now. However, the cure rate of persistent atrial fibrillation by Radiofrequency Ablation is lower than paroxysmal atrial fibrillation and we really want to know is the information that what kind of persistent atrial fibrillation ablation therapy is effective for. Therefore, it is wished the predictors of recurrence after the ablation for the persistent atrial fibrillation is confirmed, but does not yet confirm. The cause that is not confirmed seems to be present in many factors including the gene which the atrial fibrillation occurs in and persist, the change of pathology into remodeling according to progression of atrial fibrillation and strategy of the ablation corresponding to them. Left atrium diameter, Duration of atrial fibrillation and Cardiac Function that are involved deeply in atrial muscle and electric remodeling, and Ablation strategy corresponding to them are considered based on the conventional report. It can be stated now, however, that persistent atrial fibrillation patients with some degree (although this “some degree” has not been clearly defined) of enlarged left atrium diameter, prolonged atrial fibrillation duration, or decreased cardiac function may also revert to sinus rhythm with Radiofrequency Ablation, more efficient treatment may be developed in the future and reversion to sinus rhythm may increase the benefit to patients. In summary, RF ablation for persistent AF is currently required with further study of the predictors of recurrence after the ablation for the persistent atrial fibrillation.

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